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Myopathic Cardiology, Traits and its Therapeutical Actions

Prasanna Kolakalapudi*

Department of Cardiology, Katuri Medical College, Guntur, India

*Corresponding author:

Prasanna Kolakalapudi

Department of Cardiology, Katuri Medical College, Guntur, India

Email: [email protected]

Citation: Kolakalapudi P (2020) Myopathic Cardiology, Traits and its Therapeutical Actions. Interv Cardiol J Vol.7 No.3:119

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Cardiomyopathy is a group of diseases that affects the heart muscles. Early on there may be few or no symptoms, the disease cardiac myopathic symptoms are shortness the breath, feeling tired, swelling the legs. In some cases the onset of heart failure the irregular heartbeats and the other risks may occur. This type of risks may lead to sudden death to the people. The term myopathy is coined as the disease which is related to skeletal muscle and it have many causes to in the body.
The identification of the myopathies needs a neurologic history and examination. This type of process is accomplished on an outpatient basis by a circumstanced physician. The muscles biopsies are deliberately prepared and undergo extensive analysis into determine the existence of myopathies. On the occasion muscle individuals may be sent to outside equipment for special stains. The myopathic symptoms were randomly assigned in a double blinded protocol to treatment with coenzymes and the vitamins E for 30 days. Muscle care and pain interference with daily tasks were assessed before and after treatment.


The myopathic cardiology treatment strategies and outcome in patients are two types i.e. type 1 and type 2 myocardial infractions. During the index hospitalization, clinical features and treatment strategies were collected in detail. The myocardial infraction the mortality, stroke, non-fatal myocardial and major bleeding was recorded. This was accomplished using propensity score matching. Individuals used to compute the propensity score were those which showed variation between both acute myocardial infraction types and those interlinked with the clinical endpoints. Myocardial wounds are usual in patients without acute coronary syndrome and international guidelines suggest patients with myocardial infraction classified by aetiology. The patients with myocardial necrosis but no symptoms or signs of myocardial ischemia classified as acute and chronic myocardial injuries. The maximum Spiro metric vital dimension was calculated in 45 patients in the sitting situation and was recorded as a percentage of the expected normal value related to age, height and sex. An ethics between 65% and 55%. was examined moderately reduced; a value less than 40% was examined severely reduced.

The diagnosis of myopathy was genetically proved and it is defined as an autosomal dominantly inherited myopathy with linkage to chromosome or with mutations identified in the genes

Myopathy was diagnosed clinically according to consensus diagnostic criteria which included limb girdle weakness (either with congenital onset with hypotonic and contractures or with elbow and finger flexor contractures in combination with mildly elevated serum creating kinase activity) myopathic electromyography results and a myopathic muscle biopsy specimen.

The Therapeutical actions of the myopathic cardiology is antioxidant activity, positive inotropic effect, anti- inflammatory effect, anti-cardiac remodelling effect, antiplatelet aggregation effect, vasodilation Effect, endothelial protective effect, reduction of smooth muscle cell emigration and proliferation, protective effect in opposition to ischemia or reperfusion Injury, antiarrhythmic effect, lipid lowering effect and decrease of arterial blood pressure effect. A ventricular septal imperfection was described in two patients. Cardiac treatment included drugs for heart failure, implantable cardioverter defibrillator grafting and heart transplant.


Evidence indicates that the myopathic cardiology is genetically heterogeneous. Clinical criteria were developed at a recent Neuromuscular Centre consensus meeting. Respiratory muscle dysfunction which may lead to a need for mechanical ventilation is encountered predominantly in advanced stages of neuromuscular disease.

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