Abstract

Evaluation of Impact of Congestive Cardiac Failure on Selected Hematological Markers of Patients in Enugu, Nigeria

Congestive Cardiac Failure (CCF) is a great threat to humanity whenever it occurs. It occurs more often in the elderly and is more in women. It brings about drastic alterations in the entire systems including the haematological system of the human body. Haematological markers are great indicators for health and disease. The study was done to determine the impact of congestive cardiac failure on haematological markers of the patients. The study was done in a Secondary health institution in Enugu. A total of fifty (50) subjects were selected for the study, 25 subjects were congestive cardiac failure subjects aged 74 ± 2.5 years and 25 subjects were apparently healthy individuals aged matched as the control. About 2 ml of venous blood sample was drawn from each subjects into EDTA anticoagulated container and used for the haematological investigations by Mindray BC-5300. The results were presented in tables as mean and standard deviation and analysed using student t-test and level of significance set at P<0.05. The results showed significant decrease (P<0.05) in ESR, WBC, Neutrophil, MCHC, significant increase (P<0.05) in lymphocyte, monocyte, basophil, RBC, haematocrit, MCV, MCH and no significant difference (P>0.05) in eosinophils of the congestive cardiac failure subjects compared to the control. The study showed reduced ESR and haemoglobinaemia which may overstress the heart. This condition is dangerous as the red cell line is highly increased as well as the white cell line. This is disastrous if not well managed. The clinicians should monitor the haematological markers especially the haemoglobin and the erythrocyte sedimentation rate in the patients to avert the danger to the patients which will correct when the patient recover from the disease.


Author(s):

Emmanuel Ifeanyi Obeagu, Blessing Chimezie Didia, Obioma Azuonwu and Getrude Uzoma Obeagu



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